{"id":66829,"date":"2024-02-14T09:09:42","date_gmt":"2024-02-14T14:09:42","guid":{"rendered":"https:\/\/olduvai.ca\/?p=66829"},"modified":"2024-02-14T09:09:42","modified_gmt":"2024-02-14T14:09:42","slug":"safe-food-additive-may-have-consequences-for-gut-microbiome","status":"publish","type":"post","link":"https:\/\/olduvai.ca\/?p=66829","title":{"rendered":"\u2018Safe\u2019 Food Additive May Have Consequences for Gut Microbiome"},"content":{"rendered":"<h3 class=\"theme-app-hidden sm:title-bold font-source my-2 text-[25px] font-medium leading-[30px] sm:text-[45px] sm:font-bold sm:leading-[54px]\"><a href=\"https:\/\/www.theepochtimes.com\/health\/safe-food-additive-may-have-consequences-for-gut-microbiome-5583801?utm_source=partner&amp;utm_campaign=ZeroHedge&amp;src_src=partner&amp;src_cmp=ZeroHedge\">\u2018Safe\u2019 Food Additive May Have Consequences for Gut Microbiome<\/a><\/h3>\n<div class=\"theme-app-hidden my-4 border-y border-[#D3D3D3] pb-4 pt-3 text-[18px] italic leading-[21px] sm:mb-[30px] sm:mt-3.5 sm:pb-2.5 sm:pt-2 sm:text-[22px] sm:not-italic sm:leading-[26px] lg:mb-[16px]\"><strong>The antimicrobial nisin used to keep foods safe from pathogens appears to be responsible for harming commensal gut microbes.\u00a0<\/strong><\/div>\n<div id=\"post_content\" class=\"post_content\" data-post-content=\"true\">\n<p>A naturally derived antibiotic that helps preserve food by killing any threatening pathogens has kept our food safe for decades.<\/p>\n<div class=\"my-5\">The <a class=\"health-article-hover-class\" href=\"https:\/\/apps.who.int\/food-additives-contaminants-jecfa-database\/Home\/Chemical\/572\" target=\"_blank\" rel=\"noopener\">World Health Organization<\/a> and even <a class=\"health-article-hover-class\" href=\"https:\/\/www.cspinet.org\/page\/chemical-cuisine-ratings\" target=\"_blank\" rel=\"noopener\">watchdog groups<\/a> have classified this additive, called nisin, as safe. Nisin is a lantibiotic\u2014a peptide-derived antimicrobial agent synthesized from its natural form\u2014first <a class=\"health-article-hover-class\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/B9781845698119500062\" target=\"_blank\" rel=\"noopener\">discovered in 1928<\/a> and commonly used in products such as cheese, beer, processed meats, and dipping sauces.<\/div>\n<div class=\"my-5\">Nisin is made when bovine milk or whey is <a class=\"health-article-hover-class\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0924224409000594#:~:text=Nisin%20is%20manufactured%20via%20fermentation,milled%20to%20yield%20small%20particles.\" target=\"_blank\" rel=\"noopener\">fermented by strains<\/a> of Lactococcus lactis that are concentrated and processed into small particles. In addition to being used as a food preservative, nisin can be found in beauty products, pharmaceuticals, and pet products.<\/div>\n<div class=\"my-5\">However, new research raises concern about whether nisin could be harmful to the human gut microbiome\u2014the community of bacteria, viruses, fungi, and other microorganisms that work symbiotically to help with body functions such as digestion and immune response.<strong>Potency of Lantibiotics<\/strong><\/p>\n<p>A study published in <a class=\"health-article-hover-class\" href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acschembio.3c00577\" target=\"_blank\" rel=\"noopener\">ACS Chemical Biology<\/a> examined human gut bacteria genomes to identify those that resemble nisin. Researchers then produced six lantibiotics, including four new ones, and tested them on microbes. While the researchers found that these new candidates kill pathogenic bacteria, they also discovered that they have varying effects on commensal (favorable) microbes, too.<\/div>\n<div class=\"my-5\">\u201cEven though it might be very effective in preventing food contamination, it might also have a greater impact on our human gut microbes,\u201d lead author <a class=\"health-article-hover-class\" href=\"https:\/\/pamerlab.uchicago.edu\/zhang-profile\/\" target=\"_blank\" rel=\"noopener\">Zhenrun \u201cJerry\u201d Zhang<\/a>, a postdoctoral scholar and director of the Duchossois Family Institute at the University of Chicago, said in a statement.<\/div>\n<p>\u2026click on the above link to read the rest\u2026<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u2018Safe\u2019 Food Additive May Have Consequences for Gut Microbiome The antimicrobial nisin used to keep foods safe from pathogens appears to be responsible for harming commensal gut microbes.\u00a0 A naturally derived antibiotic that helps preserve food by killing any threatening pathogens has kept our food safe for decades. The World Health Organization and even watchdog [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4],"tags":[34121,34122,21124,34123,34124,16350],"class_list":["post-66829","post","type-post","status-publish","format-standard","hentry","category-environment","tag-amy-denney","tag-food-additive","tag-food-safety","tag-gut-microbiome","tag-lantibiotics","tag-the-epoch-times"],"_links":{"self":[{"href":"https:\/\/olduvai.ca\/index.php?rest_route=\/wp\/v2\/posts\/66829","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/olduvai.ca\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/olduvai.ca\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/olduvai.ca\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/olduvai.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=66829"}],"version-history":[{"count":1,"href":"https:\/\/olduvai.ca\/index.php?rest_route=\/wp\/v2\/posts\/66829\/revisions"}],"predecessor-version":[{"id":66830,"href":"https:\/\/olduvai.ca\/index.php?rest_route=\/wp\/v2\/posts\/66829\/revisions\/66830"}],"wp:attachment":[{"href":"https:\/\/olduvai.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=66829"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/olduvai.ca\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=66829"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/olduvai.ca\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=66829"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}